Implantable tissue isolation chambers for analyzing tumor dynamics in vivo

  • Clinical Condition
    •    Recruitment of new blood vessels is central to tumor progression.
    • Studying tumors and normal tissue is experimentally challenging due to rapidly changing events in a short distance and a dense 3D space.
  • Current Practice
    •    Tumor implanted directly in host tissue or in culture.
    • No vascular/tumor biology detail.
  • Solution
    •  Partially confined tumors within biocompatible and optically clear tissue isolation chambers.
    • Provisional patent.
    • Applicability to in vivo drug testing and cancer research.